Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-tosylamide-2-phenylethyl chloromethylketone | - |
Sus scrofa | |
antipain | - |
Sus scrofa | |
iodoacetamide | - |
Sus scrofa | |
iodoacetic acid | - |
Sus scrofa | |
leupeptin | Ki: 0.15-0.17 nM | Sus scrofa | |
N-ethylmaleimide | - |
Sus scrofa | |
N-tosyl-lysyl chloromethylketone | - |
Sus scrofa | |
phenylmethanesulfonyl fluoride | no inhibition at 0.5 mM | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.204 | 0.225 | benzyloxycarbonyl-Phe-Arg-4-methylcoumaryl-7-amide | - |
Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
24000 | 31000 | isoenzyme I, gel filtration, SDS-PAGE | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Proteins + H2O | Sus scrofa | turnover of intracellular proteins | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Sus scrofa | - |
Storage Stability | Organism |
---|---|
-20°C, 4 months, stable | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin-7-amide | - |
Sus scrofa | benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin | - |
? | |
Proteins + H2O | turnover of intracellular proteins | Sus scrofa | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
63 | 71 | benzyloxycarbonyl-Phe-Arg-4-methylcoumaryl-7-amide | - |
Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
- |
Sus scrofa |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
4 | 6.7 | stable | Sus scrofa |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000015 | 0.000017 | leupeptin | - |
Sus scrofa |