Activating Compound | Comment | Organism | Structure |
---|---|---|---|
interferon-gamma | - |
Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CA-074-Me | - |
Mus musculus | |
lipopolysaccharides | - |
Mus musculus | |
NO | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | RAW-264.7 cell culture supernatant | Mus musculus | - |
- |
lysosome | - |
Mus musculus | 5764 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
Balb/c mice | - |
Mus musculus BALB/c | - |
Balb/c mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A20 cell | B cell line | Mus musculus | - |
B-cell lymphoma cell | - |
Mus musculus | - |
B-lymphocyte | - |
Mus musculus | - |
RAW-264.7 cell | - |
Mus musculus | - |
T-lymphocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide + H2O | - |
Mus musculus | N-benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin | - |
? | |
N-benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide + H2O | - |
Mus musculus BALB/c | N-benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cat B | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | exposure of GSH-depleted B cells to NO-releasing compounds lowers their capacity to present a reduced and alkylated lysozyme due to inhibition of cathepsin B by NO, overview. Cells with a normal GSH content are protected from this inhibition | Mus musculus |
physiological function | cathepsin B activity is necessary for TAP-HEL, a reduced and alkylated lysozyme, processing, it is essential for generation of the HEL-derived antigenic peptide recognized by B9.1 cells | Mus musculus |