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Literature summary for 3.4.22.14 extracted from

  • McDowall, M.A.
    The action of proteinase A 2 of Actinidia chinensis on the B-chain of oxidized insulin (1973), Biochim. Biophys. Acta, 293, 226-231.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Actinidia chinensis
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Insulin B-chain + H2O the enzyme cleaves most readily the carboxyl peptide bonds of those residues of the B-chain acylated by large hydrophobic residues - Val, Leu, or Phe, but not Tyr - and also the Arg22-Gly23 bond Actinidia chinensis ?
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