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Literature summary for 3.4.22.26 extracted from

  • Moore, W.R.
    The purification and properties of cancer procoagulant from murine tumors (1992), Biochem. Biophys. Res. Commun., 184, 819-824.
    View publication on PubMed
Search for more literature for 3.4.22.26

Inhibitors

Inhibitors Comment Organism Structure
(D)-Phe-Pro-(D,L)-(4'-guanidino)-Phe-trifluoromethyl ketone
-
 Mus musculus
(D)-Phe-Pro-(D,L)-Lys-trifluoromethyl ketone weak Mus musculus
(D)-Phe-Pro-Arg-chloromethyl ketone
-
 Mus musculus
2-Vinylpyridine
-
 Mus musculus
benzoxycarbonyl-Lys-CHN2
-
 Mus musculus
HgCl2 Hg2+ Mus musculus
iodoacetamide
-
 Mus musculus
leupeptin
-
 Mus musculus
additional information no inhibition by cystamine, benzoxycarbonyl-Val-Phe Mus musculus
N-benzyloxycarbonyl-Phe-Ala-CHN2
-
 Mus musculus
phenylmethylsulfonyl fluoride
-
 Mus musculus
trans-epoxysuccinyl-L-leucyl-amido(4-guanidino)butane i.e. E-64, thiol protease inhibitor, factor X protects Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface loosely anchored on outside of cells Mus musculus 9986
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
 Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
10000
-
 mouse, Lewis lung tumor, gel filtration, procoagulant interacts with Sephacryl-200 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
factor X + H2O Mus musculus thiol protease with thrombin-like specificity ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
from Lewis lung tumor cells Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
amelanotic melanoma cell amelanotic tumor (F10 and B16, mouse) Mus musculus
-
B-16 cell
-
 Mus musculus
-
carcinoma cell
-
 Mus musculus
-
Lewis lung carcinoma cell
-
 Mus musculus
-
additional information unique in tumor Mus musculus
-

Storage Stability

Storage Stability Organism
4°C, inactivation within 1 week Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(D)-Leu-(L)-Ser-(L)-Thr-(L)-Arg p-nitroanilide + H2O
-
 Mus musculus ?
-
 ?
Factor X + H2O
-
 Mus musculus Factor Xa + ?
-
 ?
factor X + H2O thiol protease with thrombin-like specificity Mus musculus ?
-
 ?
thrombin TH + H2O
-
 Mus musculus ?
-
 ?

Subunits

Subunits Comment Organism
monomer mouse, Lewis lung tumor, SDS-PAGE Mus musculus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mus musculus