Literature summary for 3.4.22.41 extracted from

Tang, C.H.; Lee, J.W.; Galvez, M.G.; Robillard, L.; Mole, S.E.; Chapman, H.A.
Murine cathepsin F deficiency causes neuronal lipofuscinosis and late-onset neurological disease (2006), Mol. Cell. Biol., 26, 2309-2316.

Search for more literature for 3.4.22.41

Cloned(Commentary)

Cloned (Comment)	Organism
DNA and amino acid sequence determination and analysis	Mus musculus

Protein Variants

Protein Variants	Comment	Organism
additional information	generation of cat F-deficient mice by homologous recombination, the mutation leads to weight loss and death within 6 months, deficient neurons accumulate eosiniophilic granules causing neuronal ceroid lipofuscinosis beginning as early as 6 weeks of age, overview	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
JPM565	radioactive-labeling by 125I, irrevrsible inhibitor of papin-type cathepsins, active site labeling	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
lysosome	-	Mus musculus	5764	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
31000	-	x * 31000, SDS-PAGE	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	C57BL/6J and 129 SVJ mice	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
central nervous system	distribution, overview	Mus musculus	-
cerebellum	-	Mus musculus	-
neuron	-	Mus musculus	-
stem cortex	-	Mus musculus	-

Subunits

Subunits	Comment	Organism
?	x * 31000, SDS-PAGE	Mus musculus

Synonyms

Synonyms	Comment	Organism
cat F	-	Mus musculus

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Release 2023.1 (January 2023)