Any feedback?
Literature summary for 3.4.22.B14 extracted from
- Further in vitro characterization of mouse hepatitis virus papain-like proteinase 1: cleavage sequence requirements within pp1a (2002), J. Neurovirol., 8, 143-149.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Murine coronavirus | the virus can regulate in vivo proteinase activity through self inactivation of PLP-1. The lack of p50 production in cells infected with the mouse hepatitis virus strain JHM may regulate PLP-1 activity differently from MHV-59 | ? | - |
? |  |
| additional information | Murine coronavirus JHM | the virus can regulate in vivo proteinase activity through self inactivation of PLP-1. The lack of p50 production in cells infected with the mouse hepatitis virus strain JHM may regulate PLP-1 activity differently from MHV-59 | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Murine coronavirus | P0C6V1 | - |
- |
| Murine coronavirus | P0C6V1 | i.e. mouse hepatitis virus | - |
| Murine coronavirus | P0C6V1 | strain A59 | - |
| Murine coronavirus JHM | P0C6V1 | - |
- |
| Murine coronavirus JHM | P0C6V1 | i.e. mouse hepatitis virus | - |
| Murine coronavirus JHM | P0C6V1 | strain A59 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the virus can regulate in vivo proteinase activity through self inactivation of PLP-1. The lack of p50 production in cells infected with the mouse hepatitis virus strain JHM may regulate PLP-1 activity differently from MHV-59 | Murine coronavirus | ? | - |
? | |
| additional information | the virus can regulate in vivo proteinase activity through self inactivation of PLP-1. The lack of p50 production in cells infected with the mouse hepatitis virus strain JHM may regulate PLP-1 activity differently from MHV-59 | Murine coronavirus JHM | ? | - |
? | |
| ORF 1a polyprotein + H2O | - |
Murine coronavirus | ? | - |
? | |
| ORF 1a polyprotein + H2O | - |
Murine coronavirus JHM | ? | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
