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Literature summary for 3.4.22.B14 extracted from

  • Bonilla, P.J.; Hughes, S.A.; Pinon, J.D.; Weiss, S.R.
    Characterization of the leader papain-like proteinase of MHV-A59: identification of a new in vitro cleavage site (1995), Virology, 209, 489-497.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
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Murine coronavirus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ORF 1a polyprotein + H2O Murine coronavirus the enzyme is involved in processing of ORF 1a polyprotein into mature replicase-related polypeptides ?
-
?
ORF 1a polyprotein + H2O Murine coronavirus JHM the enzyme is involved in processing of ORF 1a polyprotein into mature replicase-related polypeptides ?
-
?

Organism

Organism UniProt Comment Textmining
Murine coronavirus P0C6V1 i.e. mouse hepatitis virus
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Murine coronavirus P0C6V1 strain A59
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Murine coronavirus JHM P0C6V1 i.e. mouse hepatitis virus
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Murine coronavirus JHM P0C6V1 strain A59
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ORF 1a polyprotein + H2O cleavage sites are: Gly247-/-Val248 and Gly821-/-Val822. PLP-1 is responsible for the cleavage of the amino-terminal protein p28 Murine coronavirus ?
-
?
ORF 1a polyprotein + H2O the enzyme is involved in processing of ORF 1a polyprotein into mature replicase-related polypeptides Murine coronavirus ?
-
?
ORF 1a polyprotein + H2O cleavage sites are: Gly247-/-Val248 and Gly821-/-Val822. PLP-1 is responsible for the cleavage of the amino-terminal protein p28 Murine coronavirus JHM ?
-
?
ORF 1a polyprotein + H2O the enzyme is involved in processing of ORF 1a polyprotein into mature replicase-related polypeptides Murine coronavirus JHM ?
-
?