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Literature summary for 3.4.22.B50 extracted from

  • Ziebuhr, J.; Schelle, B.; Karl, N.; Minskaia, E.; Bayer, S.; Siddell, S.G.; Gorbalenya, A.E.; Thiel, V.
    Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication (2007), J. Virol., 81, 3922-3932.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Human coronavirus 229E
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information proteolytic processing of the human coronavirus 229E. PL2pro is able to cleave the nsp1-nsp2 cleavage site. PL2pro plays a universal and essential proteolytic role that appears to be assisted by the PL1pro paralog at specific sites Human coronavirus 229E ?
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Synonyms

Synonyms Comment Organism
papain-like accessory protease
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Human coronavirus 229E
PL2pro
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Human coronavirus 229E