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Literature summary for 3.5.1.11 extracted from

  • Gong, X.; Su, E.; Wang, P.; Wei, D.
    Alcaligenes faecalis penicillin G acylase-catalyzed enantioselective acylation of dl-phenylalanine and derivatives in aqueous medium (2011), Tetrahedron Lett., 52, 5398-5402.
No PubMed abstract available
Search for more literature for 3.5.1.11

Organism

Organism UniProt Comment Textmining
Alcaligenes faecalis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-chloro-L-phenylalanine + phenylacetamide
-
 Alcaligenes faecalis N-[(4-chlorophenyl)acetyl]-L-tyrosine + NH3
-
 ?
4-fluoro-L-phenylalanine + phenylacetamide
-
 Alcaligenes faecalis N-[(4-fluorophenyl)acetyl]-L-tyrosine + NH3
-
 ?
4-methyl-L-phenylalanine + phenylacetamide
-
 Alcaligenes faecalis N-[(4-methylphenyl)acetyl]-L-tyrosine + NH3
-
 ?
4-nitro-L-phenylalanine + phenylacetamide
-
 Alcaligenes faecalis N-[(4-nitrophenyl)acetyl]-L-tyrosine + NH3
-
 ?
L-phenylalanine + (2S)-2-amino-2-phenylethanamide
-
 Alcaligenes faecalis N-[(2S)-2-amino-2-phenylacetyl]-L-phenylalanine + NH3
-
 ?
L-phenylalanine + (2S)-2-hydroxy-2-phenylethanamide
-
 Alcaligenes faecalis N-[(2S)-2-hydroxy-2-phenylacetyl]-L-phenylalanine + NH3
-
 ?
L-phenylalanine + 2-(4-hydroxyphenyl)acetamide
-
 Alcaligenes faecalis N-[(4-hydroxyphenyl)acetyl]-L-phenylalanine + NH3
-
 ?
L-phenylalanine + methyl (2S)-hydroxy(4-hydroxyphenyl)ethanoate
-
 Alcaligenes faecalis N-[(2S)-2-hydroxy-2-phenylacetyl]-L-phenylalanine + methanol
-
 ?
L-phenylalanine + methyl (4-hydroxyphenyl)acetate
-
 Alcaligenes faecalis N-[(4-hydroxyphenyl)acetyl]-L-phenylalanine + methanol
-
 ?
L-phenylalanine + methyl phenylacetate
-
 Alcaligenes faecalis N-phenylacetyl-L-phenylalanine + methanol
-
 ?
L-phenylalanine + N-[(2S)-2-amino-2-phenylacetyl]-L-phenylalanine
-
 Alcaligenes faecalis N-[(2S)-2-amino-2-phenylacetyl]-L-phenylalanine + methanol
-
 ?
L-phenylalanine + phenylacetamide
-
 Alcaligenes faecalis N-phenylacetyl-L-phenylalanine + NH3
-
 ?
L-tyrosine + phenylacetamide
-
 Alcaligenes faecalis N-(phenylacetyl)-L-tyrosine + NH3
-
 ?
penicillin G + H2O
-
 Alcaligenes faecalis phenyl acetic acid + 6-aminopenicillanate
-
 ?

Synonyms

Synonyms Comment Organism
penicillin G acylase
-
 Alcaligenes faecalis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8 10 nearly 80% activity at pH 11 Alcaligenes faecalis