Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-phenyl isoindolin-1-one | - |
Mus musculus | |
2-phenylbenzo[d] isoxazol-3(2H)-one | - |
Mus musculus | |
2-phenylbenzo[d]isothiazol-3(2H)-one | - |
Mus musculus | |
6-diazo-5-oxo-Lnorleucine | time-dependent inhibition | Mus musculus | |
apomorphine | competitive inhibition, i.e. 5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol | Mus musculus | |
Berberine | - |
Mus musculus | |
bis-2-(5-phenylacetimido-1,2,4-thiadiazol-2-yl)ethyl sulfide | uncompetitive inhibition | Mus musculus | |
chelerythrine | competitive inhibition, i.e. 1,2-dimethoxy-N-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium | Mus musculus | |
ebselen | mixed non-competitive inhibition, i.e. 2-phenyl-1,2-benzisoselenazol-3[2H]-one | Mus musculus | |
nitidine | - |
Mus musculus | |
norsanguinarine | - |
Mus musculus | |
R(-)-apocodeine | - |
Mus musculus | |
R(-)-propylnorapomorphine | - |
Mus musculus | |
sanguinarine | - |
Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamine + H2O | Mus musculus | - |
L-glutamate + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamine + H2O | - |
Mus musculus | L-glutamate + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GAC | c-type glutaminase | Mus musculus |
GLA | liver glutaminase | Mus musculus |
GLS | - |
Mus musculus |
KGA | kidney-type glutaminase | Mus musculus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000015 | - |
ebselen | pH and temperature not specified in the publication | Mus musculus | |
0.000125 | - |
bis-2-(5-phenylacetimido-1,2,4-thiadiazol-2-yl)ethyl sulfide | pH and temperature not specified in the publication | Mus musculus | |
0.00027 | - |
chelerythrine | pH and temperature not specified in the publication | Mus musculus | |
0.00232 | - |
apomorphine | pH and temperature not specified in the publication | Mus musculus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000009 | - |
pH and temperature not specified in the publication | Mus musculus | ebselen | |
0.00003 | - |
pH and temperature not specified in the publication | Mus musculus | chelerythrine | |
0.0001 | - |
pH and temperature not specified in the publication | Mus musculus | sanguinarine | |
0.0006 | - |
pH and temperature not specified in the publication | Mus musculus | apomorphine | |
0.0009 | - |
pH and temperature not specified in the publication | Mus musculus | R(-)-propylnorapomorphine | |
0.004 | - |
pH and temperature not specified in the publication | Mus musculus | R(-)-apocodeine | |
0.009 | - |
pH and temperature not specified in the publication | Mus musculus | nitidine | |
0.02 | - |
pH and temperature not specified in the publication | Mus musculus | 2-phenylbenzo[d] isoxazol-3(2H)-one | |
0.1 | - |
IC50 above 0.1 mM, pH and temperature not specified in the publication | Mus musculus | Berberine | |
0.1 | - |
IC50 above 0.1 mM, pH and temperature not specified in the publication | Mus musculus | 2-phenyl isoindolin-1-one | |
0.1 | - |
IC50 above 0.1 mM, pH and temperature not specified in the publication | Mus musculus | norsanguinarine |