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Literature summary for 3.5.1.5 extracted from
- Mutational and computational evidence that a nickel-transfer tunnel in UreD is used for activation of Klebsiella aerogenes urease (2015), Biochemistry, 54, 6392-6401 .
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ni2+ | the nickel-containing enzyme requires four accessory proteins for proper active site metalation. The metallochaperone UreE delivers nickel to UreG, a GTPase that forms a UreD/UreF/UreG complex, which binds to urease apoprotein via UreD. A molecular tunnel in UreD is a direct facilitator of nickel transfer into urease | Klebsiella aerogenes |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Klebsiella aerogenes | - |
- |
- |
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Release 2023.1 (January 2023)
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