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Literature summary for 3.5.1.9 extracted from

  • Santti, R.S.
    Formamidase in guinea pig liver II. Effect of aliphatic alcohols (1969), Hoppe-Seyler's Z. Physiol. Chem., 350, 1279-1285.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
butanol activation e.g. between 0.75-2.5%, v/v, depending on substrate Cavia porcellus
ethanol activation e.g. between 2.5-12%, v/v, depending on substrate Cavia porcellus
methanol optimal activation e.g. between 5-15%, v/v, depending on substrate Cavia porcellus
Propanol activation e.g. between 1.5-5%, v/v, depending on substrate Cavia porcellus

Inhibitors

Inhibitors Comment Organism Structure
acetone inhibition up to 10%, v/v Cavia porcellus
dimethyl sulfoxide inhibition up to 10%, v/v Cavia porcellus
dioxane inhibition up to 10%, v/v Cavia porcellus
N,N-Dimethylformamide inhibition up to 10%, v/v Cavia porcellus
Urea 25% inhibition at 2 M Cavia porcellus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N-formyl-L-kynurenine + H2O Cavia porcellus formation of alcohol esters in the presence of alcohols L-kynurenine + formate
-
?
N-formylanthranilic acid + H2O Cavia porcellus formation of alcohol esters in the presence of alcohols formate + anthranilic acid
-
?

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Cavia porcellus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetanilide + H2O formation of alcohol esters in the presence of alcohols Cavia porcellus acetate + aniline
-
?
N-acetylanthranilic acid + H2O formation of alcohol esters in the presence of alcohols Cavia porcellus acetate + anthranilic acid
-
?
N-formyl-L-kynurenine + H2O formation of alcohol esters in the presence of alcohols Cavia porcellus L-kynurenine + formate
-
?
N-formylanthranilic acid + H2O formation of alcohol esters in the presence of alcohols Cavia porcellus formate + anthranilic acid
-
?