Crystallization (Comment) | Organism |
---|---|
in complex with inhibitors 2(S)-amino-6-boronohexanoic acid or S-(2-boronoethyl)-L-cysteine | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2(S)-amino-6-boronohexanoic acid | Kd-value 5 nM, complete inhibition of enzyme in cytoplasmic extracts of myeloid suppressor cells by 0.05 mM | Homo sapiens | |
S-(2-boronoethyl)-L-cysteine | Kd-value 270 nM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.02 | - |
L-arginine | pH 9.5 | Homo sapiens | |
0.08 | - |
L-arginine | pH 8.5 | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | binuclear cluster | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P05089 | isoform arginase I | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
L-arginine + H2O = L-ornithine + urea | H141 as general acid to protonate the leaving amino group of L-ornithine during catalysis | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + H2O | - |
Homo sapiens | L-ornithine + urea | - |
? |