Any feedback?
Literature summary for 3.5.3.6 extracted from
- Arginine deiminase modulates endothelial tip cells via excessive synthesis of reactive oxygen species (2011), Biochem. Soc. Trans., 39, 1376-1381.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HMEC cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| arginine deiminase | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | ADI modulates the angiogenic activity of endothelial tip cells. By arginine depletion, ADI disturbs actin filament in endothelial tip cells, causing disordered migratory direction and decreased migration ability | Homo sapiens |
| physiological function | ADI induces excessive synthesis of reactive oxygen species, and activates caspase 8-, but not caspase 9-, dependent apoptosis in endothelial cells | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
