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Literature summary for 3.5.4.12 extracted from

  • Dosseva.I.M.; Tomov, T.H.
    Stabilizing effect of ethyleneglycol on deoxycytidylate deaminase in relation to thermal and ultraviolet inactivation (1975), Dokl. Bolg. Akad. Nauk, 28, 241-244.
No PubMed abstract available
Search for more literature for 3.5.4.12

General Stability

General Stability Organism
2-mercaptoethanol stabilizes Mus musculus
dCTP or glycerol stabilize Mus musculus
ethyleneglycol, 20%, stabilizes against thermal and UV inactivation and denaturation factors with different mechanism of action Mus musculus
glycerol stabilizes Mus musculus
some free nucleotides, most effective dCTP, stabilize Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dCMP + H2O Mus musculus one of the regulatory enzymes of DNA biosynthesis dUMP + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 Ehrlich's ascites tumor cells and various gastrointestinal tumors
-

Purification (Commentary)

Purification (Comment) Organism
partial, Ehrlich's ascites tumor cells Mus musculus

Reaction

Reaction Comment Organism Reaction ID
dCMP + H2O = dUMP + NH3 highly regulated allosteric enzyme Mus musculus
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dCMP + H2O
-
 Mus musculus dUMP + NH3
-
 ?
dCMP + H2O one of the regulatory enzymes of DNA biosynthesis Mus musculus dUMP + NH3
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
additional information
-
 ethyleneglycol stabilizes against thermal and UV inactivation Mus musculus
43
-
 in the presence of ethyleneglycol: 100% stable Mus musculus
50
-
 ethyleneglycol stabilizes against thermal inactivation, when temperature increases to 50°C, leads to certain increase in specific activity Mus musculus