BRENDA - Enzyme Database show
show all sequences of 3.5.4.3

Crystallization and preliminary crystallographic analysis of Bacillus subtilis guanine deaminase

Chang Yu Ju, C.Y.; Huang Chun Hsian, H.C.; Hu Chih Yun, H.C.; Liaw Shwu Hue, L.S.; Acta Crystallogr. Sect. D 60, 1152-1154 (2004)

Data extracted from this reference:

Crystallization (Commentary)
Crystallization
Organism
in absence and presence of inhibitor hypoxanthine, growth of crystals in 30% polyethylene glycol
Bacillus subtilis
Inhibitors
Inhibitors
Commentary
Organism
Structure
hypoxanthine
-
Bacillus subtilis
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Bacillus subtilis
-
-
-
Crystallization (Commentary) (protein specific)
Crystallization
Organism
in absence and presence of inhibitor hypoxanthine, growth of crystals in 30% polyethylene glycol
Bacillus subtilis
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
hypoxanthine
-
Bacillus subtilis
Other publictions for EC 3.5.4.3
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
734510
Trautwein-Schult
Arxula adeninivorans recombina ...
Blastobotrys adeninivorans, Blastobotrys adeninivorans LS3
J. Mol. Microbiol. Biotechnol.
24
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2014
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1
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1
2
2
3
3
2
-
7
-
-
1
-
-
-
2
4
16
1
1
-
2
2
2
-
1
-
-
1
-
-
-
1
-
-
-
-
-
1
-
2
2
3
3
2
-
-
-
1
-
-
2
4
16
1
1
-
2
2
2
-
1
1
1
-
-
1
-
-
733339
Bitra
Identification of function and ...
Nitrosomonas europaea
Biochemistry
52
3512-3522
2013
-
-
-
1
3
-
-
-
-
1
-
2
-
2
-
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2
1
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1
3
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1
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2
1
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-
-
-
-
-
-
-
-
-
-
-
1
1
733496
Tantravedi
Analogs of iso-azepinomycin as ...
Oryctolagus cuniculus
Bioorg. Med. Chem.
21
4893-4903
2013
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-
-
-
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13
-
-
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2
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1
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1
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-
1
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-
-
-
733480
Chakraborty
Investigations into specificit ...
Oryctolagus cuniculus
Bioorg. Med. Chem. Lett.
22
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2012
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-
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3
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1
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2
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1
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1
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3
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3
3
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1
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1
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1
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719723
Guzman
Transcriptional regulation of ...
Klebsiella pneumoniae
J. Bacteriol.
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2011
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1
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1
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1
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1
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1
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1
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Fernandez
Identification of small molecu ...
Homo sapiens, Oryctolagus cuniculus, Rattus norvegicus
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2010
2
3
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21
1
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3
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5
-
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1
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1
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3
-
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-
-
-
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7
-
-
2
3
-
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21
7
1
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3
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-
1
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
3
3
-
-
-
712293
Seffernick
Bacterial ammeline metabolism ...
Bradyrhizobium japonicum, Bradyrhizobium japonicum USDA 110, Escherichia coli, Homo sapiens, Pseudomonas putida, Pseudomonas putida KT 2240
J. Bacteriol.
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2010
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18
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1
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2
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-
-
18
-
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-
-
-
-
-
-
-
4
4
-
-
-
712380
Kim
Guanine deaminase functions as ...
Drosophila melanogaster, Drosophila melanogaster Oregon-R
J. Biol. Chem.
284
23426-23435
2009
-
-
1
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9
2
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1
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5
-
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1
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1
2
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10
1
1
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2
1
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-
1
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-
1
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-
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9
-
2
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1
-
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1
-
1
2
-
10
1
1
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2
1
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1
-
1
1
-
2
2
713411
Murphy
Alteration of enzyme specifici ...
Homo sapiens
Proc. Natl. Acad. Sci. USA
106
9215-9220
2009
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1
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2
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689944
Fernandez
Structural characterization of ...
Rattus norvegicus
Proteins
70
873-881
2008
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1
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7
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1
1
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1
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2
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3
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2
1
1
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1
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1
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7
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1
1
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1
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3
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2
1
1
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1
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697984
Medici
Arthrobacter oxydans as a bioc ...
Pseudarthrobacter oxydans
FEMS Microbiol. Lett.
289
20-26
2008
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1
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4
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688614
Yao
Catalytic mechanism of guanine ...
Bacillus subtilis
J. Phys. Chem. B
111
4200-4210
2007
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667985
Ujjinamatada
Design of inhibitors against g ...
Oryctolagus cuniculus
Bioorg. Med. Chem. Lett.
16
5551-5554
2006
-
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3
2
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1
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1
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1
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1
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5
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3
5
2
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1
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2
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2
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1
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1
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688300
Sannomiya
A histochemical and immunohist ...
Homo sapiens, Rattus norvegicus
J. Med. Invest.
53
246-254
2006
-
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4
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14
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14
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688301
Kubo
Histochemical and immunohistoc ...
Homo sapiens
J. Med. Invest.
53
264-270
2006
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2
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2
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9
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9
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1
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652554
Liaw
Crystal structure of Bacillus ...
Bacillus subtilis
J. Biol. Chem.
279
35479-35485
2004
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1
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1
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1
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1
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1
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1
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-
667036
Chang Yu Ju
Crystallization and preliminar ...
Bacillus subtilis
Acta Crystallogr. Sect. D
60
1152-1154
2004
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1
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1
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2
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667182
Roberts
Estimation of guanine deaminas ...
Homo sapiens
Anal. Biochem.
324
250-257
2004
-
2
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3
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5
1
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2
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5
1
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-
671013
Saint-Marc
GUD1 (YDL238c) encodes Sacchar ...
Saccharomyces cerevisiae
Yeast
21
1359-1363
2004
-
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2
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1
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-
209603
Maynes
Identification, expression and ...
Escherichia coli, Homo sapiens
J. Bacteriol.
8
4658-4660
2000
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2
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1
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2
1
2
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4
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1
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2
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2
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2
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1
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2
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209602
Yuan
Cloning and characterization o ...
Homo sapiens, Mus musculus, Sus sp.
J. Biol. Chem.
274
8175-8180
1999
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1
1
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1
4
1
2
10
3
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5
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2
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9
1
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3
4
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1
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1
1
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1
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4
1
2
10
3
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2
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9
1
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3
4
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1
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-
209601
Rajappan
Analogues of azepinomycin as i ...
Homo sapiens, Oryctolagus cuniculus
Nucleosides Nucleotides
17
1141-1151
1998
-
1
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1
1
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2
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3
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2
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2
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1
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1
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2
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2
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734059
Stuer-Lauridsen
Purine salvage in two halophil ...
Halobacterium salinarum, Haloferax volcanii
J. Bacteriol.
180
457-463
1998
-
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2
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2
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2
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2
2
-
-
-
209600
Canbolat
Activities of adenosine deamin ...
Homo sapiens
Breast Cancer Res. Treat.
37
189-193
1996
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1
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-
-
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1
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2
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2
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1
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1
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1
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2
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1
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-
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-
-
-
-
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-
-
209539
Negishi
-
Guanosine deaminase and guanin ...
Camellia sinensis, Clostridium sp., Nicotiana tabacum, Rattus norvegicus
Biosci. Biotechnol. Biochem.
58
1277-1281
1994
3
-
-
-
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5
1
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5
1
4
-
4
-
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3
-
-
4
1
2
7
-
1
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2
-
4
-
1
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3
-
-
-
-
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5
-
1
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5
1
4
-
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3
-
4
1
2
7
-
1
-
2
-
4
-
1
-
-
-
-
-
-
-
209598
Ito
-
Histochemical and biochemical ...
Homo sapiens, Mus musculus, Rattus norvegicus
Acta Histochem.
24
591-596
1991
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1
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3
-
3
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1
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10
-
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3
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1
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3
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1
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10
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3
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209584
Kimm
-
The physicochemical properties ...
Homo sapiens, Oryctolagus cuniculus, Rattus norvegicus, Sus sp.
Korean J. Biochem.
19
39-46
1987
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-
-
-
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12
1
-
-
8
4
-
4
-
-
3
-
-
9
1
-
4
6
-
-
-
-
5
1
-
-
-
-
-
-
-
-
-
-
-
-
-
12
-
1
-
-
8
4
-
-
-
3
-
9
1
-
4
6
-
-
-
-
5
1
-
-
-
-
-
-
-
-
209585
Kimm
-
Purification and characterizat ...
Homo sapiens, Oryctolagus cuniculus, Rattus norvegicus
Korean J. Biochem.
17
139-148
1985
-
-
-
-
-
-
12
1
1
-
9
3
-
3
-
-
2
-
-
3
1
-
11
3
-
-
4
-
11
-
-
-
-
-
-
-
-
-
-
-
-
-
-
12
-
1
1
-
9
3
-
-
-
2
-
3
1
-
11
3
-
-
4
-
11
-
-
-
-
-
-
-
-
-
209586
Gupta
Isolation and characterization ...
Bos taurus, Homo sapiens, Oryctolagus cuniculus, Rattus norvegicus, Sus sp.
Arch. Biochem. Biophys.
236
266-276
1985
-
-
-
-
-
-
12
23
-
-
26
5
-
6
-
-
3
-
-
5
1
-
10
5
-
-
6
-
7
1
-
-
-
-
-
-
-
-
-
-
-
-
-
12
-
23
-
-
26
5
-
-
-
3
-
5
1
-
10
5
-
-
6
-
7
1
-
-
-
-
-
-
-
-
209587
Pugh
Studies of rabbit brain, intes ...
Bos taurus, Cavia porcellus, Homo sapiens, Oryctolagus cuniculus, Ovis ammon, Sus sp.
Comp. Biochem. Physiol. B
77
619-627
1984
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1
-
-
-
-
4
31
-
-
25
6
-
7
-
-
1
-
-
16
6
1
6
5
-
-
-
-
5
1
-
-
-
-
-
-
1
-
-
-
-
-
-
4
-
31
-
-
25
6
-
-
-
1
-
16
6
1
6
5
-
-
-
-
5
1
-
-
-
-
-
-
-
-
209588
Kim
-
Enzymatic evidence for a mitoc ...
Clostridium sp., Homo sapiens, Mus musculus, Ophiodon elongatus, Rattus norvegicus, Rattus norvegicus Sprague Dawley
Korean J. Biochem.
14
77-93
1982
-
-
-
-
-
1
11
-
-
-
-
6
-
14
-
-
1
-
-
12
5
-
6
2
-
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
11
-
-
-
-
-
6
-
-
-
1
-
12
5
-
6
2
-
1
1
-
1
-
-
-
-
-
-
-
-
-
209589
Miyamoto
Guanine deaminase from rat bra ...
Rattus norvegicus, Rattus norvegicus Wistar, Sus sp.
J. Biochem.
91
167-176
1982
5
-
-
-
-
-
2
3
1
-
4
3
-
169
-
-
1
-
-
5
1
1
5
2
-
-
-
-
1
-
-
-
-
-
-
5
-
-
-
-
-
-
-
2
-
3
1
-
4
3
-
-
-
1
-
5
1
1
5
2
-
-
-
-
1
-
-
-
-
-
-
-
-
-
209590
Kuzmits
Guanase from human liver - pur ...
Homo sapiens, Mus musculus, Rattus norvegicus
Adv. Exp. Med. Biol.
122B
183-188
1980
-
-
-
-
-
-
-
2
1
-
1
3
-
4
-
-
1
-
-
22
1
-
3
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
1
-
1
3
-
-
-
1
-
22
1
-
3
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
209591
Bergstrom
Characterization of purified g ...
Oryctolagus cuniculus
Arch. Biochem. Biophys.
194
107-116
1979
-
-
-
-
-
-
4
2
-
-
6
1
-
1
-
-
1
-
-
1
-
-
3
2
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
2
-
-
6
1
-
-
-
1
-
1
-
-
3
2
-
-
-
-
1
1
-
-
-
-
-
-
-
-
209592
Glantz
Guanine deaminase from rabbit ...
Oryctolagus cuniculus
Methods Enzymol.
51
512-517
1978
-
-
-
-
-
1
5
3
-
-
-
1
-
2
-
-
1
-
-
2
1
-
3
-
-
-
3
-
2
-
-
-
-
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-
-
-
-
-
-
-
1
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5
-
3
-
-
-
1
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-
1
-
2
1
-
3
-
-
-
3
-
2
-
-
-
-
-
-
-
-
-
209593
Rossi
Purification and properties of ...
Mus musculus, Oryctolagus cuniculus, Ovis ammon, Platyrrhini, Rattus norvegicus, Sus sp.
Biochim. Biophys. Acta
526
235-246
1978
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-
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2
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11
6
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7
-
-
1
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-
9
-
1
9
4
-
-
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-
1
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-
-
-
-
-
-
-
-
-
-
-
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2
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11
6
-
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-
1
-
9
-
1
9
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
209594
Fogle
Purification of rabbit liver g ...
Homo sapiens, Ophiodon elongatus, Oryctolagus cuniculus, Rattus norvegicus
Prep. Biochem.
5
59-77
1975
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-
-
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4
2
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8
4
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5
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1
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9
1
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4
1
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3
1
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-
-
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-
-
-
-
-
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4
-
2
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-
8
4
-
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1
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9
1
-
4
1
-
-
-
-
3
1
-
-
-
-
-
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-
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209595
Lewis
Rabbit liver guanine deaminase ...
Oryctolagus cuniculus, Rattus norvegicus
J. Biol. Chem.
249
3862-3866
1974
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-
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1
9
5
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6
2
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3
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1
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-
3
1
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4
2
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1
5
-
5
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-
1
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9
-
5
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6
2
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1
-
3
1
-
4
2
-
1
5
-
5
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-
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-
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209596
Kumar
Guanine deaminase in rat liver ...
Mus musculus, Rattus norvegicus
Biochem. J.
128
1079-1088
1972
1
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1
8
6
1
4
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2
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4
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2
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8
4
3
3
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-
2
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4
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-
1
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-
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-
1
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8
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6
1
4
-
2
-
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-
2
-
8
4
3
3
-
-
-
2
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4
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209597
Rabinowitz
Purine fermentation by Clostri ...
Clostridium sp.
J. Biol. Chem.
218
161-173
1956
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1
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2
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1
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