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Literature summary for 3.6.1.1 extracted from

  • Cooperman, B.S.
    The mechanism of action of yeast inorganic pyrophosphatase (1982), Methods Enzymol., 87, 526-548.
    View publication on PubMed
Search for more literature for 3.6.1.1

Inhibitors

Inhibitors Comment Organism Structure
Ca2P2O7
-
 Saccharomyces cerevisiae
O3PCHOHPO3
-
 Saccharomyces cerevisiae
O3PNHPO
-
 Saccharomyces cerevisiae

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ maximum activation compared to other divalent ion activators Saccharomyces cerevisiae
Zn2+ higher activation than Co2+, Mn2+ Saccharomyces cerevisiae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
32042
-
 2 * 32042, amino acid sequence Saccharomyces cerevisiae
64080
-
 amino acid sequence Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
diphosphate + H2O Saccharomyces cerevisiae
-
 2 phosphate
-
 r

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 yeast
-

Purification (Commentary)

Purification (Comment) Organism
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O hydrolysis only with Zn2+ or Mn2+ as cofactors Saccharomyces cerevisiae ?
-
 ?
diphosphate + H2O
-
 Saccharomyces cerevisiae 2 phosphate
-
 r
diphosphate + H2O high specificity with Mg2+ as cofactor Saccharomyces cerevisiae 2 phosphate
-
 r
tripolyphosphate + H2O hydrolysis only with Zn2+ or Mn2+ as cofactors Saccharomyces cerevisiae ?
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 32042, amino acid sequence Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
 Saccharomyces cerevisiae