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Literature summary for 3.6.1.54 extracted from

  • Okada, C.; Wakabayashi, H.; Kobayashi, M.; Shinoda, A.; Tanaka, I.; Yao, M.
    Crystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa (2016), Sci. Rep., 6, 32822 .
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
-
 Pseudomonas aeruginosa

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Pseudomonas aeruginosa

Protein Variants

Protein Variants Comment Organism
H10N the inactive mutant shows loss of manganese 1-binding ability Pseudomonas aeruginosa

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ contains two Mn2+ ions which are required for enzymatic activity Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine + H2O Pseudomonas aeruginosa
-
 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + UMP
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa Q9I2V0
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine + H2O
-
 Pseudomonas aeruginosa 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + UMP
-
 ?

Synonyms

Synonyms Comment Organism
LpxH
-
 Pseudomonas aeruginosa
UDP-diacylglucosamine pyrophosphohydrase
-
 Pseudomonas aeruginosa