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Literature summary for 3.6.1.7 extracted from

  • Nassi, P.; Marchetti, E.; Nediani, C.; Liguri, G.; Ramponi, G.
    Acylphosphatase induced modifications in the functional properties of erythrocyte membrane sodium pump (1993), Biochim. Biophys. Acta, 1147, 19-26.
    View publication on PubMed
Search for more literature for 3.6.1.7

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.000147
-
 Na+/K+-ATPase phosphoenzyme intermediate high affinity for this substrate Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-
Homo sapiens
-
 two isoenzymatic forms: one prevalent in skeletal and cardiac muscle, the other in red blood cells
-

Purification (Commentary)

Purification (Comment) Organism
erythrocyte isoenzyme Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
7500
-
 erythrocyte isoenzyme, substrate benzoyl phosphate, 25°C Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(Ca2+-Mg2+)-ATPase phosphorylated intermediate + H2O erythrocyte type enzyme, acylphosphorylated intermediates from human erythrocyte membrane Homo sapiens ?
-
 ?
1,3-diphosphoglycerate + H2O
-
 Homo sapiens 3-phosphoglycerate + phosphate
-
 ?
acylphosphate + H2O specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates Homo sapiens carboxylate + phosphate
-
 ?
benzoyl phosphate + H2O
-
 Homo sapiens benzoate + phosphate
-
 ?
carbamoyl phosphate + H2O
-
 Homo sapiens carbamate + phosphate
-
 ?
Na+/K+-ATPase phosphoenzyme intermediate + H2O mechanism Homo sapiens ?
-
 ?
Na+/K+-ATPase phosphoenzyme intermediate + H2O acylphosphatase can actively hydrolyze Na+/K+-ATPase phosphoenzyme Homo sapiens ?
-
 ?
Na+/K+-ATPase phosphoenzyme intermediate + H2O acylphosphatase produces a modification in the stoichiometry of the ATP driven cation transport by the Na+,K+ pump Homo sapiens ?
-
 ?
Na+/K+-ATPase phosphoenzyme intermediate + H2O from erythrocyte membrane Homo sapiens ?
-
 ?
Na+/K+-ATPase phosphoenzyme intermediate + H2O acylphosphatase significantly enhances the rate of strophantidine-sensitive ATP hydrolysis, it uncouples erythrocyte membrane N+,K+ pump Homo sapiens ?
-
 ?
Na+/K+-ATPase phosphoenzyme intermediate + H2O acylphosphatase markedly affects the functional properties of Na+,K+ pump, notably the rate of ATP hydrolysis and of cation, Na+,Rb+, transport Homo sapiens ?
-
 ?
Na+/K+-ATPase phosphoenzyme intermediate + H2O acylphosphorylated phosphoenzyme intermediate, enzyme has a high affinity for this substrate Homo sapiens ?
-
 ?
succinoyl phosphate + H2O
-
 Homo sapiens succinate + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
More two isoenzymatic forms: one prevalent in skeletal and cardiac muscle named muscle type, the other in red blood cells named erythrocyte or common type, even if both isoforms are expressed in all tissues Homo sapiens

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
100
-
 2 h: heat inactivation Homo sapiens