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Literature summary for 4.1.1.17 extracted from

  • Seidel, E.R.; Ragan, V.; Liu, L.
    Peroxynitrite inhibits the activity of ornithine decarboxylase (2001), Life Sci., 68, 1477-1483.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
peroxynitrite 0.1 mM, 50% inhibition, almost complete inhibition above 1 mM, nitration of tyrosine residues Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-ornithine Rattus norvegicus involved in polyamine biosynthesis putrescine + CO2
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant ODC Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-ornithine
-
Rattus norvegicus putrescine + CO2
-
?
L-ornithine involved in polyamine biosynthesis Rattus norvegicus putrescine + CO2
-
?

Synonyms

Synonyms Comment Organism
ODC
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Rattus norvegicus