Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.1.1.19 extracted from

  • Balbo, P.B.; Patel, C.N.; Sell, K.G.; Adcock, R.S.; Neelakantan, S.; Crooks, P.A.; Oliveira, M.A.
    Spectrophotometric and steady-state kinetic analysis of the biosynthetic arginine decarboxylase of Yersinia pestis utilizing arginine analogues as inhibitors and alternative substrates (2003), Biochemistry, 42, 15189-15196.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
agmatine
-
Yersinia pestis
D-Arg
-
Yersinia pestis
guanidine
-
Yersinia pestis
L-arginine methyl ester
-
Yersinia pestis
L-arginineamide
-
Yersinia pestis
L-argininic acid
-
Yersinia pestis
L-canavanine
-
Yersinia pestis
L-homoarginine
-
Yersinia pestis
methylguanidine
-
Yersinia pestis
N-benzylguanidine
-
Yersinia pestis
n-propylguanidine
-
Yersinia pestis
Ngamma-methyl-D-arginine
-
Yersinia pestis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.163
-
Ngamma-methyl-L-arginine pH 7.5, 37°C Yersinia pestis
0.2
-
L-Arg pH 7.5, 37°C Yersinia pestis
0.233
-
L-canavanine pH 7.5, 37°C Yersinia pestis
9.53
-
L-N5-(iminoethyl)-ornithine pH 7.5, 37°C Yersinia pestis

Organism

Organism UniProt Comment Textmining
Yersinia pestis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine
-
Yersinia pestis agmatine + CO2
-
?
L-canavanine
-
Yersinia pestis N-(3-aminopropoxy)guanidine + CO2
-
?
L-N5-(iminoethyl)-ornithine
-
Yersinia pestis N1-(2-iminoethyl)-butane-1,4-diamine + CO2
-
?
Ngamma-monomethyl-L-Arg
-
Yersinia pestis N-(3-aminopropyl)-N'-methylguanidine + CO2
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.11
-
L-canavanine pH 7.5, 37°C Yersinia pestis
0.419
-
L-N5-(iminoethyl)-ornithine pH 7.5, 37°C Yersinia pestis
1.22
-
Ngamma-methyl-L-arginine pH 7.5, 37°C Yersinia pestis
5.46
-
L-Arg pH 7.5, 37°C Yersinia pestis

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0206
-
D-Arg pH 7.5, 37°C Yersinia pestis
0.168
-
NG-methyl-D-arginine pH 7.5, 37°C Yersinia pestis
0.189
-
L-arginine methyl ester pH 7.5, 37°C Yersinia pestis
0.327
-
L-argininic acid pH 7.5, 37°C Yersinia pestis
0.427
-
L-canavanine pH 7.5, 37°C Yersinia pestis
0.897
-
L-argininamide pH 7.5, 37°C Yersinia pestis
1.4
-
N-benzylguanidine pH 7.5, 37°C Yersinia pestis
1.53
-
L-homoarginine pH 7.5, 37°C Yersinia pestis
1.93
-
n-propylguanidine pH 7.5, 37°C Yersinia pestis
2.77
-
agmatine pH 7.5, 37°C Yersinia pestis
3.09
-
methylguanidine pH 7.5, 37°C Yersinia pestis
3.39
-
guanidine pH 7.5, 37°C Yersinia pestis