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Literature summary for 4.1.1.19 extracted from
- Crystallization, X-ray diffraction and oligomeric characterization of arginine decarboxylase from Yersinia pestis, a key polyamine biosynthetic enzyme (2004), Acta Crystallogr. Sect. D, 60, 2396-2398.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed as His-tag fusion protein in Escherichia coli BL21(DE3)pLysE | Yersinia pestis |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| hanging drop vapor diffusion method, in the presence and absence of Mg2+ and pyridoxal 5-phosphate | Yersinia pestis |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Yersinia pestis |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 74000 | - |
4 * 74000, crystal structure analysis | Yersinia pestis |
| 163100 | - |
apo-ADC, light-scattering analysis | Yersinia pestis |
| 178000 | - |
holo-ADC, light-scattering analysis | Yersinia pestis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-arginine | Yersinia pestis | key enzyme in the biosynthesis of polyamines, key enzyme in the biosynthesis of putrescine, plays a role in stress response | agmatine + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Yersinia pestis | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant protein using His-tag | Yersinia pestis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-arginine | - |
Yersinia pestis | agmatine + CO2 | - |
? | |
| L-arginine | key enzyme in the biosynthesis of polyamines, key enzyme in the biosynthesis of putrescine, plays a role in stress response | Yersinia pestis | agmatine + CO2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | in solution at pH 8.0, light-scattering analysis | Yersinia pestis |
| tetramer | 4 * 74000, crystal structure analysis | Yersinia pestis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Yersinia pestis | |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Yersinia pestis | - |
- |
4.9 |
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