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Literature summary for 4.1.1.28 extracted from
- Intrastriatal inhibition of aromatic amino acid decarboxylase prevents L-DOPA-induced dyskinesia: A bilateral reverse in vivo microdialysis study in 6-hydroxydopamine lesioned rats (2008), Neurobiol. Dis., 29, 210-220.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Benserazide | intrastriatal inhibition of the enzyme prevents the appearance of L-dopa-induced dyskinetic movements at the lesioned side | Rattus norvegicus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-3,4-Dihydroxyphenylalanine | Rattus norvegicus | - |
Dopamine + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
male Wistar rats | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| striatum | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-3,4-Dihydroxyphenylalanine | - |
Rattus norvegicus | Dopamine + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AADC | - |
Rattus norvegicus |
| Aromatic amino acid decarboxylase | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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