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Literature summary for 4.1.1.28 extracted from

  • Yuwen, L.; Zhang, F.; Chen, Q.; Lin, S.; Zhao, Y.; Li, Z.
    The role of aromatic L-amino acid decarboxylase in bacillamide C biosynthesis by Bacillus atrophaeus C89 (2013), Sci. Rep., 3, 1753.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.1.28

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Bacillus atrophaeus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.35
-
 L-tryptophan pH 8.0, 35°C Bacillus atrophaeus
0.872
-
 L-phenylalanine pH 8.0, 35°C Bacillus atrophaeus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55899
-
 x * 58000, SDS-PAGE, x * 55899, calculated Bacillus atrophaeus
58000
-
 x * 58000, SDS-PAGE, x * 55899, calculated Bacillus atrophaeus

Organism

Organism UniProt Comment Textmining
Bacillus atrophaeus I0DFJ0
-
-
Bacillus atrophaeus C89 I0DFJ0
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-phenylalanine
-
 Bacillus atrophaeus 2-phenylethylamine + CO2
-
 ?
L-phenylalanine
-
 Bacillus atrophaeus C89 2-phenylethylamine + CO2
-
 ?
L-tryptophan
-
 Bacillus atrophaeus tryptamine + CO2
-
 ?
L-tryptophan
-
 Bacillus atrophaeus C89 tryptamine + CO2
-
 ?
additional information no substrate: L-tyrosine Bacillus atrophaeus ?
-
 ?
additional information no substrate: L-tyrosine Bacillus atrophaeus C89 ?
-
 ?

Subunits

Subunits Comment Organism
? x * 58000, SDS-PAGE, x * 55899, calculated Bacillus atrophaeus

pI Value

Organism Comment pI Value Maximum pI Value
Bacillus atrophaeus calculated
-
 6

General Information

General Information Comment Organism
physiological function during bacillamide C biosynthesis, the decarboxylation of L-tryptophan to tryptamine is likely conducted first under aromatic L-amino acid decarboxylase catalysis, followed by the amidation of tryptamine with the carboxylic product of non-ribosomal peptide synthetases gene cluster Bacillus atrophaeus