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Literature summary for 4.1.1.37 extracted from

  • De Verneuil, H.; Grandchamp, B.; Nordmann, Y.
    Some kinetic properties of human red cell uroporphyrinogen decarboxylase (1980), Biochim. Biophys. Acta, 611, 174-186.
    View publication on PubMed
Search for more literature for 4.1.1.37

Inhibitors

Inhibitors Comment Organism Structure
7-COOH-porphyrinogen I inhibits decarboxylation of 7-COOH-porphyrinogen III Homo sapiens
7-COOH-porphyrinogen III inhibits decarboxylation of 7-COOH-porphyrinogen I Homo sapiens
Uroporphyrinogen I inhibits decarboxylation of uroporphyrinogen III Homo sapiens
uroporphyrinogen III inhibits decarboxylation of uroporphyrinogen I, no inhibition of 7-COOH-series II porphyrinogens and 5-COOH-series II porphyrinogens decarboxylation Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00035
-
 7-COOH-porphyrinogen III
-
 Homo sapiens
0.0004
-
 uroporphyrinogen III
-
 Homo sapiens
0.0004
-
 5-COOH-porphyrinogen III
-
 Homo sapiens
0.00085
-
 7-COOH-porphyrinogen I
-
 Homo sapiens
0.0009
-
 5-COOH-porphyrinogen I
-
 Homo sapiens
0.001
-
 Uroporphyrinogen I
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-COOH-porphyrinogen I
-
 Homo sapiens Coproporphyrinogen I + CO2
-
 ?
5-COOH-porphyrinogen III
-
 Homo sapiens Coproporphyrinogen III + CO2
-
 ?
7-COOH-porphyrinogen I
-
 Homo sapiens Coproporphyrinogen I + CO2
-
 ?
7-COOH-porphyrinogen III
-
 Homo sapiens Coproporphyrinogen III + CO2
-
 ?
uroporphyrinogen I
-
 Homo sapiens coproporphyrinogen I + 4 CO2
-
 ?
Uroporphyrinogen III
-
 Homo sapiens Coproporphyrinogen III + 4 CO2
-
 ?