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Literature summary for 4.1.1.37 extracted from

  • Juknat, A.A.; Seubert, A.; Seubert, S.; Ippen, H.
    Studies on uroporphyrinogen decarboxylase of etiolated Euglena gracilis Z (1989), Eur. J. Biochem., 179, 423-428.
    View publication on PubMed
Search for more literature for 4.1.1.37

Activating Compound

Activating Compound Comment Organism Structure
dithiothreitol activates Euglena gracilis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00005
-
 uroporphyrinogen III
-
 Euglena gracilis
0.00008
-
 Uroporphyrinogen I
-
 Euglena gracilis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
54000
-
 gel filtration Euglena gracilis

Organism

Organism UniProt Comment Textmining
Euglena gracilis
-
 Z strain
-
Euglena gracilis Z
-
 Z strain
-

Purification (Commentary)

Purification (Comment) Organism
-
 Euglena gracilis

Source Tissue

Source Tissue Comment Organism Textmining

Storage Stability

Storage Stability Organism
-20°C, stable for at least 2 months, partially purified enzyme Euglena gracilis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
uroporphyrinogen I
-
 Euglena gracilis coproporphyrinogen I + 4 CO2
-
 ?
uroporphyrinogen I
-
 Euglena gracilis Z coproporphyrinogen I + 4 CO2
-
 ?
Uroporphyrinogen III
-
 Euglena gracilis Coproporphyrinogen III + 4 CO2
-
 ?
Uroporphyrinogen III
-
 Euglena gracilis Z Coproporphyrinogen III + 4 CO2
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
55
-
 10 min, 90% loss of activity Euglena gracilis
65
-
 20 min, complete loss of activity Euglena gracilis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
 coproporphyrinogen formation from uroporphyrinogen I, parzial reactions: synthesis of 4-COOH-porphyrinogen III and 6-COOH-porphyrinogen from uroporphyrinogen III Euglena gracilis
7.6
-
 partial reactions: synthesis of 6-COOH porphyrinogen and 5-COOH porphyrinogen from uroporphyrinogen I Euglena gracilis