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Literature summary for 4.1.1.4 extracted from

  • Autor, A.P.; Fridovich, I.
    The interactions of acetoacetate decarboxylase with carbonyl compounds, hydrogen cyanide, and an organic mercurial (1970), J. Biol. Chem., 245, 5214-5222.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
beta-Diketones
-
Clostridium acetobutylicum
Borohydride
-
Clostridium acetobutylicum
HCN- inhibitory synergism between cyanide and carbonyl compounds. The effectiveness in descending order: acetaldehyde, acetone, cyclohexanone, methyl ethyl ketone, 3-hexanone, diethyl ketone Clostridium acetobutylicum
p-chloromercuriphenyl sulfonate reversal by Cys Clostridium acetobutylicum

Organism

Organism UniProt Comment Textmining
Clostridium acetobutylicum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-Oxo-3-phenylpropionic acid i.e. phenylacetoacetate Clostridium acetobutylicum Acetophenone + CO2
-
?
Acetoacetate
-
Clostridium acetobutylicum Acetone + CO2
-
?