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Literature summary for 4.1.1.50 extracted from

  • Regenass, U.; Caravatti, G.; Mett, M.; Stanek, J.; Schneider, P.; Mueller, M.; Matter, A.; Vertino, P.; Porter, C.W.
    New S-adenosylmethionine decarboxylase inhibitors with potent antitumor activity (1992), Cancer Res., 52, 4712-4718.
    View publication on PubMed
Search for more literature for 4.1.1.50

Inhibitors

Inhibitors Comment Organism Structure
methylglyoxal bis(guanylhydrazone)
-
 Homo sapiens
methylglyoxal bis(guanylhydrazone)
-
 Mus musculus
additional information inhibitors with potent antitumor activity Homo sapiens
additional information inhibitors with potent antitumor activity Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine Mus musculus key enzyme in polyamine biosynthesis ?
-
 ?
S-adenosyl-L-methionine Homo sapiens key enzyme in polyamine biosynthesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
L-1210 cell
-
 Mus musculus
-
urinary bladder cancer cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine
-
 Mus musculus (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
 ?
S-adenosyl-L-methionine
-
 Homo sapiens (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
 ?
S-adenosyl-L-methionine key enzyme in polyamine biosynthesis Mus musculus ?
-
 ?
S-adenosyl-L-methionine key enzyme in polyamine biosynthesis Homo sapiens ?
-
 ?