Inhibitors | Comment | Organism | Structure |
---|---|---|---|
methylglyoxal bis(guanylhydrazone) | competitive, binds at a single site per enzyme heterodimer | Methanocaldococcus jannaschii | |
NaCNBH3 | inactivation in presence of substrate | Methanocaldococcus jannaschii |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.095 | - |
S-adenosyl-L-methionine | pH 7.5 | Methanocaldococcus jannaschii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methanocaldococcus jannaschii | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
S-adenosyl-L-methionine = S-adenosyl 3-(methylsulfanyl)propylamine + CO2 | kinetics, mechanism | Methanocaldococcus jannaschii |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine | high specificity | Methanocaldococcus jannaschii | (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2 | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | increase of turnover-number 38-fold at physiological temperature of 80°C | Methanocaldococcus jannaschii | |
0.0075 | - |
S-adenosyl-L-methionine | 22 °C, pH 7.5 | Methanocaldococcus jannaschii |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
2 | 5 | methylglyoxal bis(guanylhydrazone) | - |
Methanocaldococcus jannaschii |