Literature summary for 4.1.1.7 extracted from

Kluger, R.; Ikeda, G.; Hu, Q.; Cao, P.; Drewry, J.
Accelerating unimolecular decarboxylation by preassociated acid catalysis in thiamin-derived intermediates: implicating Bronsted acids as carbanion traps in enzymes (2006), J. Am. Chem. Soc., 128, 15856-15864.

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Organism

Organism	UniProt	Comment	Textmining
Pseudomonas putida	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
benzoylformate	-	Pseudomonas putida	benzaldehyde + CO2	-	?

Cofactor

Cofactor	Comment	Organism	Structure
thiamine diphosphate	the enzyme avoids formation of a benzoyl anion by addition of enzyme-bound thiamine diphosphate to the carbonyl group of benzoylformate, producing enzyme-bound 2-(2-mandelyl)thiamine diphosphate	Pseudomonas putida

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Release 2023.1 (January 2023)