Literature summary for 4.1.2.13 extracted from

Sherawat, M.; Tolan, D.R.; Allen, K.N.
Structure of a rabbit muscle fructose-1,6-bisphosphate aldolase A dimer variant (2008), Acta Crystallogr. Sect. D, 64, 543-550.

Search for more literature for 4.1.2.13

Crystallization (Commentary)

Crystallization (Comment)	Organism
hanging-drop vapor-diffusion method	Oryctolagus cuniculus

Protein Variants

Protein Variants	Comment	Organism
D128V	mutation, mimicking the clinically important D128G mutation in humans	Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-fructose 1,6-bisphosphate	Oryctolagus cuniculus	aldolase is involved in the metabolism of fructose, converting fructose 1-phosphate to dihydroxyacetone phosphate and glyceraldehyde	dihydroxyacetone phosphate + glyceraldehyde 3-phosphate	-	r

Organism

Organism	UniProt	Comment	Textmining
Oryctolagus cuniculus	P00883	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Oryctolagus cuniculus

Source Tissue

Source Tissue	Comment	Organism	Textmining
muscle	-	Oryctolagus cuniculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-fructose 1,6-bisphosphate	aldolase is involved in the metabolism of fructose, converting fructose 1-phosphate to dihydroxyacetone phosphate and glyceraldehyde	Oryctolagus cuniculus	dihydroxyacetone phosphate + glyceraldehyde 3-phosphate	-	r

Subunits

Subunits	Comment	Organism
dimer	rabbit muscle D128V aldolase. The D128V mutation causes aldolase to lose intermolecular contacts with the neighbouring subunit at one of the two interfaces of the tetramer	Oryctolagus cuniculus
tetramer	wild-type	Oryctolagus cuniculus

Synonyms

Synonyms	Comment	Organism
fructose-1,6-bisphosphate aldolase A	-	Oryctolagus cuniculus

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Release 2023.1 (January 2023)