Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | - |
Streptococcus suis | 9986 | - |
cytoplasm | - |
Neisseria meningitidis | 5737 | - |
cytoplasm | - |
Mycobacterium tuberculosis | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-fructose 1,6-bisphosphate | Neisseria meningitidis | - |
glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
D-fructose 1,6-bisphosphate | Mycobacterium tuberculosis | - |
glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
D-fructose 1,6-bisphosphate | Streptococcus suis | - |
glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
D-fructose 1,6-bisphosphate | Streptococcus suis SS9 | - |
glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Neisseria meningitidis | - |
- |
- |
Streptococcus pneumoniae | - |
- |
- |
Streptococcus pneumoniae WU2 | - |
- |
- |
Streptococcus suis | - |
- |
- |
Streptococcus suis SS9 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-fructose 1,6-bisphosphate | - |
Neisseria meningitidis | glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
D-fructose 1,6-bisphosphate | - |
Mycobacterium tuberculosis | glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
D-fructose 1,6-bisphosphate | - |
Streptococcus suis | glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? | |
D-fructose 1,6-bisphosphate | - |
Streptococcus suis SS9 | glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FBA | - |
Neisseria meningitidis |
FBA | - |
Streptococcus pneumoniae |
FBA | - |
Mycobacterium tuberculosis |
FBA | - |
Streptococcus suis |
fructose-1,6-bisphosphate aldolase | - |
Neisseria meningitidis |
fructose-1,6-bisphosphate aldolase | - |
Streptococcus pneumoniae |
fructose-1,6-bisphosphate aldolase | - |
Mycobacterium tuberculosis |
fructose-1,6-bisphosphate aldolase | - |
Streptococcus suis |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in the Embden-Meyerhof-Parnas glycolytic pathway and in gluconeogenesis | Mycobacterium tuberculosis |
metabolism | the enzyme is involved in the Embden-Meyerhof-Parnas glycolytic pathway and in gluconeogenesis | Streptococcus suis |
physiological function | the enzyme is required for optimal adhesion to human cells | Neisseria meningitidis |
physiological function | conserved glycolytic enzyme with virulence functions in bacteria. It is involved in the Embden-Meyerhof-Parnas (EMP) glycolytic pathway and in gluconeogenesis. Additional it functions beyond its housekeeping role in central metabolism. Fructose-1,6-bisphosphate aldolase is immunogenic in Streptococcus suis SS9 | Streptococcus suis |
physiological function | conserved glycolytic enzyme with virulence functions in bacteria. It is involved in the Embden-Meyerhof-Parnas (EMP) glycolytic pathway and in gluconeogenesis. Additional it functions beyond its housekeeping role in central metabolism. The enzyme from Mycobacterium tuberculosis binds human plasminogen | Mycobacterium tuberculosis |
physiological function | conserved glycolytic enzyme with virulence functions in bacteria. It is involved in the Embden-Meyerhof-Parnas (EMP) glycolytic pathway and in gluconeogenesis. Additional it functions beyond its housekeeping role in central metabolism. The enzyme from Neisseria meningitidis is dispensable for survival of, but required for optimal adhesion to human cells | Neisseria meningitidis |
physiological function | conserved glycolytic enzyme with virulence functions in bacteria. It is involved in the Embden-Meyerhof-Parnas (EMP) glycolytic pathway and in gluconeogenesis. Additional it functions beyond its housekeeping role in central metabolism. The Pneumococcal enzyme is an immunogenic adhesin which binds Flamingo cadherin receptor | Streptococcus pneumoniae |