Literature summary for 4.2.1.1 extracted from

Cronk, J.D.; Endrizzi, J.A.; Cronk, M.R.; O'Neill, J.W.; Zhang, K.Y.J.
Crystal structure of E. coli beta-carbonic anhydrase, an enzyme with a n unusual pH-dependent activity (2001), Protein Sci., 10, 911-922.

Search for more literature for 4.2.1.1

Cloned(Commentary)

Cloned (Comment)	Organism
overexpressed in transformed Escherichia coli cultures, expression in yeast, complements the growth defect in a yeast beta-CA knockout in Saccharomyces cerevisiae DELTA NCE103	Escherichia coli

Crystallization (Commentary)

Crystallization (Comment)	Organism
2 different tetragonal crystal forms, form 1 space group P4(2)2(1)2, unit cell dimensions a : b : 68.54 A, c : 85.88A, form 2 space group P4(3)22, a : : b : 81.24 A, c : 162.14 A	Escherichia coli

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	active-site zinc	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
H2CO3	Escherichia coli	-	CO2 + H2O	-	r

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	P61517	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
H2CO3	-	Escherichia coli	CO2 + H2O	-	r

Subunits

Subunits	Comment	Organism
tetramer	-	Escherichia coli

Synonyms

Synonyms	Comment	Organism
beta-CA	-	Escherichia coli
beta-carbonic anhydrase	-	Escherichia coli
CA	-	Escherichia coli
carbonate hydrolase	-	Escherichia coli
carbonic anhydrase	-	Escherichia coli
ECCA	-	Escherichia coli

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Release 2023.1 (January 2023)