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Literature summary for 4.2.1.1 extracted from
- Entrapment of carbon dioxide in the active site of carbonic anhydrase II (2008), J. Biol. Chem., 283, 30766-30771.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3)pLysS cells | Homo sapiens |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| holoenzyme and apoenzyme are crystallized by hanging drop vapour diffusion method, using 1.3 M sodium citrate, 100 mM Tris-HCl, pH 7.8 | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| p-(aminomethyl)-benzene-sulfonamide | a CAII inhibitor | Homo sapiens |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | the holoenzyme contains Zn2+ | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P00918 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| agarose resin column chromatography | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CO2 + H2O | - |
Homo sapiens | H2CO3 | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CAII | - |
Homo sapiens |
| carbonic anhydrase II | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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