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Literature summary for 4.2.1.1 extracted from

  • Bertucci, A.; Zoccola, D.; Tambutte, S.; Vullo, D.; Supuran, C.T.
    Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines (2010), Bioorg. Med. Chem., 18, 2300-2303.
    View publication on PubMed
Search for more literature for 4.2.1.1

Activating Compound

Activating Compound Comment Organism Structure
1-(2-aminoethyl)-piperazine activation constant of 0.0115 mM Stylophora pistillata
2-(2-aminoethyl)pyridine activation constant of 0.107 mM Stylophora pistillata
2-pyridyl-methylamine activation constant of 0.126 mM Stylophora pistillata
4-(2-aminoethyl)-morpholine activation constant of 0.064 mM Stylophora pistillata
4-amino-L-phenylalanine activation constant of 0.0101 mM Stylophora pistillata
D-Dopa activation constant of 0.089 mM Stylophora pistillata
D-Dopa best activator, with an activation constant of 0.00018 mM Stylophora pistillata
D-His activation constant of 0.026 mM Stylophora pistillata
D-Phe activation constant of 0.021 mM Stylophora pistillata
D-Trp activation constant of 0.019 mM Stylophora pistillata
histamine activation constant of 0.12 mM Stylophora pistillata
L-adrenaline activation constant of 0.047 mM Stylophora pistillata
L-Dopa activation constant of 0.015 mM Stylophora pistillata
L-His activation constant of 0.028 mM Stylophora pistillata
L-Phe activation constant of 0.034 mM Stylophora pistillata
L-Trp activation constant of 0.00321 mM Stylophora pistillata
L-Tyr activation constant of 0.031 mM Stylophora pistillata
serotonin activation constant of 0.056 mM Stylophora pistillata

Organism

Organism UniProt Comment Textmining
Stylophora pistillata
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO2 + H2O
-
 Stylophora pistillata H2CO3
-
 r

Synonyms

Synonyms Comment Organism
secretory carbonic anhydrase
-
 Stylophora pistillata
STPCA
-
 Stylophora pistillata

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
340000
-
 CO2 in the absence of L-Trp and D-Trp, at 25°C and pH 7.5 Stylophora pistillata
640000
-
 CO2 in the presence of 0.01 mM D-Trp, at 25°C and pH 7.5 Stylophora pistillata
920000
-
 CO2 in the presence of 0.01 mM L-Trp, at 25°C and pH 7.5 Stylophora pistillata