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Literature summary for 4.2.1.24 extracted from

  • Gupta, P.; Jain, M.; Sarangthem, J.; Gadre, R.
    Inhibition of 5-aminolevulinic acid dehydratase by mercury in excised greening maize leaf segments (2013), Plant Physiol. Biochem., 62, 63-69.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
5,5'-dithio(bis-2-nitrobenzoic acid)
-
Zea mays
Hg2+ the inhibition caused by 0.37 mM Hg2+ is alleviated by addition of 10 mM KNO3. 10 mM NH4Cl and 5 mM sucrose increase the inhibitory effect of Hg2+ on enzyme activity, while 10 mM levulinic acid and 0.0001 mM 5,5'-dithio(bis-2-nitrobenzoic acid) glutamine and glutathione decrease it Zea mays
levulinic acid competitive inhibitor, 8% residual activity at 20 mM Zea mays

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.347
-
5-aminolevulinate in the presence of Hg2+, at pH 8.2 and 37°C Zea mays
0.532
-
5-aminolevulinate in the absence of Hg2+, at pH 8.2 and 37°C Zea mays

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5-aminolevulinate Zea mays
-
porphobilinogen + H2O
-
?

Organism

Organism UniProt Comment Textmining
Zea mays
-
cultivar GSF-2
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
Zea mays
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-aminolevulinate
-
Zea mays porphobilinogen + H2O
-
?

Synonyms

Synonyms Comment Organism
5-aminolevulinic acid dehydratase
-
Zea mays
ALAD
-
Zea mays