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Literature summary for 4.2.1.47 extracted from
- Purification of guanosine 5'-diphosphate d-mannose oxidoreductase from Phaseolus vulgaris (1972), Biochim. Biophys. Acta, 276, 85-93.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | 50% inhibition | Phaseolus vulgaris |  |
| Co2+ | 90% inhibition | Phaseolus vulgaris | |
| GDP-D-glucose | Ki: 0.084 mM | Phaseolus vulgaris | |
| GMP | 90% inhibition | Phaseolus vulgaris | |
| GTP | Ki: 0.186 mM | Phaseolus vulgaris | |
| ITP | 90% inhibition | Phaseolus vulgaris | |
| Mn2+ | 90% inhibition | Phaseolus vulgaris | |
| Ni2+ | 90% inhibition | Phaseolus vulgaris | |
| p-hydroxymercuribenzoate | - |
Phaseolus vulgaris | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.028 | - |
GDPmannose | - |
Phaseolus vulgaris | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 120000 | - |
sedimentation equilibrium centrifugation | Phaseolus vulgaris |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GDPmannose | Phaseolus vulgaris | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Phaseolus vulgaris | - |
Phaseolus aureus, mung bean | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Phaseolus vulgaris |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -15°C, 70% ammonium sulfate solution, several weeks | Phaseolus vulgaris |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GDP-mannose | - |
Phaseolus vulgaris | GDP-4-dehydro-6-deoxy-D-mannose + H2O | - |
? | |
| GDPmannose | - |
Phaseolus vulgaris | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Phaseolus vulgaris |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5 | 9.2 | - |
Phaseolus vulgaris |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.084 | - |
GDP-D-glucose | - |
Phaseolus vulgaris | |
| 0.186 | - |
GTP | - |
Phaseolus vulgaris | |
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