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Literature summary for 4.2.1.8 extracted from
- The role of iron in the activation of mannonic and altronic acid hydratases, two Fe-requiring hydro-lyases (1987), Eur. J. Biochem., 166, 623-630.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Escherichia coli |  |
| alpha-picolinate | - |
Escherichia coli | |
| EDTA | - |
Escherichia coli | |
| iodoacetate | - |
Escherichia coli | |
| nitrilotriacetic acid | - |
Escherichia coli | |
| PCMB | - |
Escherichia coli | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe2+ | required, upon inactivation the enzyme incorporates a single Fe atom, it contains no Fe-S core, the incorporated iron is losely bound | Escherichia coli | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 203.1 | - |
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-Mannonate | - |
Escherichia coli | 2-Dehydro-3-deoxy-D-gluconate + H2O | - |
? | |
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