Literature summary for 4.2.3.146 extracted from

Zhang, X.;, Shang, G.; Gu, L.; Shen Y.
Crystallization and preliminary X-ray diffraction analysis of the diterpene cyclooctatin synthase (CYC) from Streptomyces sp. LZ35 (2014), Acta Crystallogr. Sect. F, 70, 366-369.

Search for more literature for 4.2.3.146

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Streptomyces sp.

Crystallization (Commentary)

Crystallization (Comment)	Organism
sitting drop vapor diffusion method, using 0.8 M NaH2PO4/K2HPO4 pH 7.8	Streptomyces sp.

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
geranylgeranyl diphosphate + H2O	Streptomyces sp.	-	cyclooctat-9-en-7-ol + diphosphate	-	?
geranylgeranyl diphosphate + H2O	Streptomyces sp. LZ35	-	cyclooctat-9-en-7-ol + diphosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptomyces sp.	-	-	-
Streptomyces sp. LZ35	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
Ni-chelating Sepharose affinity column chromatography and Superdex 200gel filtration	Streptomyces sp.

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
geranylgeranyl diphosphate + H2O	-	Streptomyces sp.	cyclooctat-9-en-7-ol + diphosphate	-	?
geranylgeranyl diphosphate + H2O	-	Streptomyces sp. LZ35	cyclooctat-9-en-7-ol + diphosphate	-	?

Synonyms

Synonyms	Comment	Organism
CYC	-	Streptomyces sp.
diterpene cyclooctatin synthase	-	Streptomyces sp.

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Release 2023.1 (January 2023)