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Literature summary for 4.2.99.18 extracted from

  • Izumi, T.; Brown, D.B.; Naidu, C.V.; Bhakat, K.K.; Macinnes, M.A.; Saito, H.; Chen, D.J.; Mitra, S.
    Two essential but distinct functions of the mammalian abasic endonuclease (2005), Proc. Natl. Acad. Sci. USA, 102, 5739-5743.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus the enzyme has two distinct roles in the repair of oxidative DNA damage and in gene regulation. Absolute requirement of the enzyme for cell survival, presumably to protect against spontaneous oxidative DNA damage ?
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?

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme has two distinct roles in the repair of oxidative DNA damage and in gene regulation. Absolute requirement of the enzyme for cell survival, presumably to protect against spontaneous oxidative DNA damage Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
abasic endonuclease
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Mus musculus