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Literature summary for 4.3.1.24 extracted from

  • Crosby, J.
    Synthesis of optically active compounds: A large scale perspective (1991), Tetrahedron, 47, 4789-4846.
No PubMed abstract available
Search for more literature for 4.3.1.24

Application

Application Comment Organism
synthesis production of L-phenylalanine, which is used in the manufacture of the artificial sweetener aspartame and in parenteral nutrition, it is also used as a building block for the synthesis of the macrolide antibiotic rutamycin B Rhodotorula mucilaginosa
synthesis production of L-phenylalanine, which is used in the manufacture of the artificial sweetener aspartame and in parenteral nutrition, it is also used as a building block for the synthesis of the macrolide antibiotic rutamycin B Rhodococcus rubra

Organism

Organism UniProt Comment Textmining
Rhodococcus rubra
-
 Genex 1983
-
Rhodotorula mucilaginosa
-
 Genex 1986
-

Oxidation Stability

Oxidation Stability Organism
Due to the instability of the enzyme towards oxygen, the biotransformation is performed under anaerobic, static conditions Rhodotorula mucilaginosa
Due to the instability of the enzyme towards oxygen, the biotransformation is performed under anaerobic, static conditions Rhodococcus rubra

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
trans-cinnamic acid + NH3
-
 Rhodotorula mucilaginosa L-phenylalanine
-
 ?
trans-cinnamic acid + NH3
-
 Rhodococcus rubra L-phenylalanine
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
-
 Rhodotorula mucilaginosa
25
-
-
 Rhodococcus rubra

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
10.6
-
-
 Rhodotorula mucilaginosa
10.6
-
-
 Rhodococcus rubra