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Literature summary for 4.3.2.1 extracted from
- Substrate-induced inactivation of argininosuccinate lyase by monofluorofumarate and difluorofumarate (1983), Biochemistry, 22, 3729-3735.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| acetylenedicarboxylate | - |
Bos taurus |  |
| difluorofumarate | pseudo-first-order process | Bos taurus | |
| monofluorofumarate | reversible, pseudo-first-order process | Bos taurus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.046 | - |
difluorofumarate | - |
Bos taurus | |
| 0.067 | - |
fumarate | - |
Bos taurus | |
| 1.4 | - |
monofluorofumarate | - |
Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| argininosuccinate | - |
Bos taurus | fumarate + L-Arg | - |
? | |
| argininosuccinate | - |
Bos taurus | fumarate + L-Arg | - |
r | |
| difluorofumarate + L-Arg | - |
Bos taurus | ? | - |
? | |
| fumarate + L-Arg | - |
Bos taurus | argininosuccinate | - |
r | |
| monofluorofumarate + L-Arg | - |
Bos taurus | ? | - |
? | |
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