Literature summary for 4.3.3.7 extracted from

Selli, A.; Crociani, F.; DiGioia, D.; Fava, F.; Crisetig, G.; Matteuzzi, D.
Regulation of dihydrodipicolinate synthase and diaminopimelate decarboxylase activity in Bacillus stearothermophilus (1994), Ital. J. Biochem., 43, 29-35.

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Inhibitors

Inhibitors	Comment	Organism	Structure
isoleucine	not inhibitory	Geobacillus stearothermophilus
L-lysine	no inhibition	Geobacillus stearothermophilus
additional information	not inhibitory: L-Thr, L-Met	Geobacillus stearothermophilus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-aspartate-4-semialdehyde + pyruvate	Geobacillus stearothermophilus	first enzyme in the meso-diaminopimelate and L-lysine branch of the aspartate pathway	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Geobacillus stearothermophilus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-aspartate-4-semialdehyde + pyruvate	-	Geobacillus stearothermophilus	dihydrodipicolinate + H2O	-	?
L-aspartate-4-semialdehyde + pyruvate	first enzyme in the meso-diaminopimelate and L-lysine branch of the aspartate pathway	Geobacillus stearothermophilus	?	-	?

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
45	-	-	Geobacillus stearothermophilus

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
9	-	-	Geobacillus stearothermophilus

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Release 2023.1 (January 2023)