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Literature summary for 4.4.1.20 extracted from

  • Nicholson, D.W.; Ali, A.; Vaillancourt, J.P.; Calaycay, J.R.; Mumford, R.A.; Zamboni, R.J.; Ford-Hutchinson, A.W.
    Purification to homogeneity and the N-terminal sequence of human leukotriene C4 synthase: a homodimeric glutathione S-transferase composed of 18-kDa subunits (1993), Proc. Natl. Acad. Sci. USA, 90, 2015-2019.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.4.1.20

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
39200
-
 gel filtration Homo sapiens
180000
-
 2 * 180000, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HL-60 cell monocytic leukemia cell line Homo sapiens
-
lung
-
 Homo sapiens
-
monocyte
-
 Homo sapiens
-
THP-1 cell monocytic leukemia cell line Homo sapiens
-
U-937 cell monocytic leukemia cell line Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.135
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
leukotriene A4 + glutathione
-
 Homo sapiens leukotriene C4 + H2O
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 180000, SDS-PAGE Homo sapiens