Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.6.1.2 extracted from

  • Oppermann, M.; Dao, V.T.; Suvorava, T.; Bas, M.; Kojda, G.
    Effect of oral organic nitrates on expression and activity of vascular soluble guanylyl cyclase (2008), Br. J. Pharmacol., 155, 335-342.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.6.1.2

Inhibitors

Inhibitors Comment Organism Structure
NO long acting NO donors pentaerythrityl tetranitrate and isosorbide mononitrate have a significant impact on the regulation of vascular sGC expression and activity, overview Mus musculus
NO long acting NO donors pentaerythrityl tetranitrate and isosorbide mononitrate have a significant impact on the regulation of vascular sGC expression and activity, overview Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-
cytosol
-
 Oryctolagus cuniculus 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP Mus musculus the enzyme is involved in vasorelaxation, NO acts as a signalling molecule regulating sGC expression in a negative feedback loop, overview 3',5'-cyclic GMP + diphosphate
-
 ?
GTP Oryctolagus cuniculus the enzyme is involved in vasorelaxation, NO acts as a signalling molecule regulating sGC expression in a negative feedback loop, overview 3',5'-cyclic GMP + diphosphate
-
 ?
GTP Mus musculus C57BL/6 the enzyme is involved in vasorelaxation, NO acts as a signalling molecule regulating sGC expression in a negative feedback loop, overview 3',5'-cyclic GMP + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 C57BL/6 mice
-
Mus musculus C57BL/6
-
 C57BL/6 mice
-
Oryctolagus cuniculus
-
 New Zealand white rabbits
-

Source Tissue

Source Tissue Comment Organism Textmining
aorta
-
 Oryctolagus cuniculus
-
lung
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP
-
 Mus musculus 3',5'-cyclic GMP + diphosphate
-
 ?
GTP
-
 Oryctolagus cuniculus 3',5'-cyclic GMP + diphosphate
-
 ?
GTP the enzyme is involved in vasorelaxation, NO acts as a signalling molecule regulating sGC expression in a negative feedback loop, overview Mus musculus 3',5'-cyclic GMP + diphosphate
-
 ?
GTP the enzyme is involved in vasorelaxation, NO acts as a signalling molecule regulating sGC expression in a negative feedback loop, overview Oryctolagus cuniculus 3',5'-cyclic GMP + diphosphate
-
 ?
GTP
-
 Mus musculus C57BL/6 3',5'-cyclic GMP + diphosphate
-
 ?
GTP the enzyme is involved in vasorelaxation, NO acts as a signalling molecule regulating sGC expression in a negative feedback loop, overview Mus musculus C57BL/6 3',5'-cyclic GMP + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
sGC
-
 Mus musculus
sGC
-
 Oryctolagus cuniculus
soluble guanylyl cyclase
-
 Mus musculus
soluble guanylyl cyclase
-
 Oryctolagus cuniculus