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Literature summary for 4.6.1.2 extracted from

  • Szmidt-Jaworska, A.; Jaworski, K.; Kopcewicz, J.
    Effect of light on soluble guanylyl cyclase activity in Pharbitis nil seedlings (2008), J. Photochem. Photobiol. B Biol., 93, 9-15.
    View publication on PubMed
Search for more literature for 4.6.1.2

Activating Compound

Activating Compound Comment Organism Structure
additional information sGC is influenced by the light conditions, overview Ipomoea nil
NO NO stimulates elevation of endogenous cGMP in Pharbitis nil, which allows for stimulation of flower bud formation in non-inductive conditions Ipomoea nil
sodium nitroprusside via NO production Ipomoea nil
YC-1
-
 Ipomoea nil

Inhibitors

Inhibitors Comment Organism Structure
additional information sGC is influenced by the light conditions, overview Ipomoea nil
NS-2028 a potent sGC inhibitor Ipomoea nil

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.5
-
 GTP pH 7.6, 30°C Ipomoea nil

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Ipomoea nil 5829
-
additional information subcellular localization Ipomoea nil
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ sGC requires a cation cofactor Ipomoea nil
Mn2+ sGC requires a cation cofactor Ipomoea nil

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
 x * 40000, SDS-PAGE Ipomoea nil

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP Ipomoea nil
-
 3',5'-cyclic GMP + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Ipomoea nil Q0PY32 i.e. Ipomoea nil
-

Source Tissue

Source Tissue Comment Organism Textmining
cotyledon
-
 Ipomoea nil
-
hypocotyl low enzyme content Ipomoea nil
-
additional information tissue distribution, overview Ipomoea nil
-
root
-
 Ipomoea nil
-
seedling
-
 Ipomoea nil
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.00000045
-
 activity in cotyledons Ipomoea nil
0.00000048
-
 activity in seedlings Ipomoea nil

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP
-
 Ipomoea nil 3',5'-cyclic GMP + diphosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 40000, SDS-PAGE Ipomoea nil

Synonyms

Synonyms Comment Organism
soluble guanylate cyclase
-
 Ipomoea nil

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
-
 Ipomoea nil

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
20 35 temperature profile, overview Ipomoea nil

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
 assay at Ipomoea nil