Protein Variants | Comment | Organism |
---|---|---|
D155R | mutant enzyme has intact isomerase activity and cyclosporin A-binding activity. When complexed to cyclosporin A, the mutant enzyme displays only reduced affinity for calcineurin and much decreased inhibition of calcineurin phosphatase activity | Homo sapiens |
D158R | mutant enzyme has intact isomerase activity and cyclosporin A-binding activity. When complexed to cyclosporin A, the mutant enzyme displays only reduced affinity for calcineurin and much decreased inhibition of calcineurin phosphatase activity | Homo sapiens |
G77H | mutant enzyme has intact isomerase activity and cyclosporin A-binding activity. When complexed to cyclosporin A, the mutant enzyme displays only reduced affinity for calcineurin and much decreased inhibition of calcineurin phosphatase activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | cyclophilin B complexed to cyclosporin A inhibits phosphatase activity of recombinant human calcineurin | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Cyclophilin B | - |
Homo sapiens |
CyPB | - |
Homo sapiens |