Inhibitors | Comment | Organism | Structure |
---|---|---|---|
FK506 | 0.0005 mM, almost complete inhibition | Corynebacterium glutamicum |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.059 | - |
N-succinyl-Ala-Leu-(cis)-Pro-Phe-4-nitroanilide | pH 7.5, temperature not specified in the publication | Corynebacterium glutamicum | |
0.104 | - |
N-succinyl-Ala-Ala-(cis)-Pro-Phe-4-nitroanilide | pH 7.5, temperature not specified in the publication | Corynebacterium glutamicum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Corynebacterium glutamicum | P42458 | - |
- |
Corynebacterium glutamicum ATCC 13032 | P42458 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-succinyl-Ala-Ala-(cis)-Pro-Phe-4-nitroanilide | - |
Corynebacterium glutamicum | N-succinyl-Ala-Ala-(trans)-Pro-Phe-4-nitroanilide | - |
? | |
N-succinyl-Ala-Ala-(cis)-Pro-Phe-4-nitroanilide | - |
Corynebacterium glutamicum ATCC 13032 | N-succinyl-Ala-Ala-(trans)-Pro-Phe-4-nitroanilide | - |
? | |
N-succinyl-Ala-Leu-(cis)-Pro-Phe-4-nitroanilide | - |
Corynebacterium glutamicum | N-succinyl-Ala-Leu-(trans)-Pro-Phe-4-nitroanilide | - |
? | |
N-succinyl-Ala-Leu-(cis)-Pro-Phe-4-nitroanilide | - |
Corynebacterium glutamicum ATCC 13032 | N-succinyl-Ala-Leu-(trans)-Pro-Phe-4-nitroanilide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Cgl0830 | - |
Corynebacterium glutamicum |
FK506-binding protein | - |
Corynebacterium glutamicum |
FkpA | - |
Corynebacterium glutamicum |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
58 | - |
N-succinyl-Ala-Leu-(cis)-Pro-Phe-4-nitroanilide | pH 7.5, temperature not specified in the publication | Corynebacterium glutamicum | |
172 | - |
N-succinyl-Ala-Ala-(cis)-Pro-Phe-4-nitroanilide | pH 7.5, temperature not specified in the publication | Corynebacterium glutamicum |
General Information | Comment | Organism |
---|---|---|
physiological function | FkpA delays the aggregation of citrate synthase in vitro and has a positive effect on the activity and temperature range of citrate synthase in vitro. Deletion of FkpA causes a 50% reduced biomass yield compared to that of the wild type when grown at 37°C, whereas there is only a 10% reduced biomass yield at the optimal growth temperature of 30°C accompanied by accumulation of 7 mM L-glutamate and 22 mM 2-oxoglutarate | Corynebacterium glutamicum |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
600 | - |
N-succinyl-Ala-Leu-(cis)-Pro-Phe-4-nitroanilide | pH 7.5, temperature not specified in the publication | Corynebacterium glutamicum | |
1700 | - |
N-succinyl-Ala-Ala-(cis)-Pro-Phe-4-nitroanilide | pH 7.5, temperature not specified in the publication | Corynebacterium glutamicum |