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Literature summary for 5.3.3.2 extracted from

  • Berthelot, K.; Estevez, Y.; Deffieux, A.; Peruch, F.
    Isopentenyl diphosphate isomerase: A checkpoint to isoprenoid biosynthesis (2012), Biochimie, 94, 1621-1634.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ dependent on Homo sapiens
Mg2+ dependent on Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
24500
-
x * 24500, SDS-PAGE Escherichia coli
26300
-
x * 26300, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isopentenyl diphosphate Homo sapiens
-
dimethylallyl diphosphate
-
?
isopentenyl diphosphate Escherichia coli
-
dimethylallyl diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli Q46822
-
-
Homo sapiens Q13907 isoform 1 and isoform 2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isopentenyl diphosphate
-
Homo sapiens dimethylallyl diphosphate
-
?
isopentenyl diphosphate
-
Escherichia coli dimethylallyl diphosphate
-
?

Subunits

Subunits Comment Organism
? x * 26300, SDS-PAGE Homo sapiens
? x * 24500, SDS-PAGE Escherichia coli

Synonyms

Synonyms Comment Organism
type 1 IPP isomerase
-
Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
Homo sapiens
7.4
-
-
Escherichia coli

pI Value

Organism Comment pI Value Maximum pI Value
Homo sapiens isoelectric focusing
-
5.9
Escherichia coli isoelectric focusing
-
5.9

General Information

General Information Comment Organism
metabolism IPP isomerase activity is a rate-limiting step in terpenoid synthesis Homo sapiens
metabolism IPP isomerase activity is a rate-limiting step in terpenoid synthesis Escherichia coli