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Literature summary for 5.3.3.4 extracted from

  • Skiba, A.; Hecht, V.; Pieper, D.H.
    Formation of protoanemonin from 2-chloro-cis,cis-muconate by the combined action of muconate cycloisomerase and muconolactone isomerase (2002), J. Bacteriol., 184, 5402-5409.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.3.3.4

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.66
-
 (4R,5R)-5-chloro-3-methylmuconolactone pH 7.5, 25°C Cupriavidus necator
3.6
-
 (4S)-2-chloromuconolactone pH 7.5, 25°C Cupriavidus necator
6
-
 (4S)-muconolactone pH 7.5, 25°C Cupriavidus necator
10.3
-
 (4R,5S)-5-chloromuconolactone pH 7.5, 25°C Cupriavidus necator

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Cupriavidus necator formation of protoanemonin from 2-chloro-cis,cis-muconate by the combined action of muconate cycloisomerase and muconolactone isomerase ?
-
 ?
additional information Cupriavidus necator JMP 134-1 formation of protoanemonin from 2-chloro-cis,cis-muconate by the combined action of muconate cycloisomerase and muconolactone isomerase ?
-
 ?

Organism

Organism UniProt Comment Textmining
Cupriavidus necator
-
 JMP134
-
Cupriavidus necator JMP 134-1
-
 JMP134
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(4R,5R)-5-chloro-3-methylmuconolactone
-
 Cupriavidus necator ?
-
 ?
(4R,5R)-5-chloro-3-methylmuconolactone
-
 Cupriavidus necator JMP 134-1 ?
-
 ?
(4R,5S)-5-chloromuconolactone
-
 Cupriavidus necator ?
-
 ?
(4R,5S)-5-chloromuconolactone
-
 Cupriavidus necator JMP 134-1 ?
-
 ?
(4S)-2-chloromuconolactone
-
 Cupriavidus necator ?
-
 ?
(4S)-2-chloromuconolactone
-
 Cupriavidus necator JMP 134-1 ?
-
 ?
(4S)-muconolactone
-
 Cupriavidus necator 5-oxo-3,4-dihydrofuran-2-acetate
-
 ?
(4S)-muconolactone
-
 Cupriavidus necator JMP 134-1 5-oxo-3,4-dihydrofuran-2-acetate
-
 ?
additional information formation of protoanemonin from 2-chloro-cis,cis-muconate by the combined action of muconate cycloisomerase and muconolactone isomerase Cupriavidus necator ?
-
 ?
additional information formation of protoanemonin from 2-chloro-cis,cis-muconate by the combined action of muconate cycloisomerase and muconolactone isomerase Cupriavidus necator JMP 134-1 ?
-
 ?

Synonyms

Synonyms Comment Organism
MLI
-
 Cupriavidus necator

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.03 0.55 (4S)-2-chloromuconolactone pH 7.5, 25°C Cupriavidus necator
7.17
-
 (4S)-2-chloromuconolactone pH 7.5, 25°C Cupriavidus necator
42.5
-
 (4R,5R)-5-chloro-3-methylmuconolactone pH 7.5, 25°C Cupriavidus necator
286
-
 (4S)-muconolactone pH 7.5, 25°C Cupriavidus necator
5950
-
 (4R,5S)-5-chloromuconolactone pH 7.5, 25°C Cupriavidus necator